PARP2 antibody

Catalog No. ABIN5703726

This anti-PARP2 antibody is a Rabbit Polyclonal antibody detecting PARP2 in WB and ELISA. Suitable for Human and Mouse.

Quick Overview for PARP2 antibody (ABIN5703726)

Target: PARP2 (Poly (ADP-Ribose) Polymerase 2 (PARP2))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PARP2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-PARP2 Antibody

Purpose: PARP2 antibody

Immunogen: poly (ADP-ribose) polymerase 2

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for PARP2

Target: PARP2 (Poly (ADP-Ribose) Polymerase 2 (PARP2))

Alternative Name: PARP2

Background:

Synonyms: Poly [ADP-ribose] polymerase 2 (PARP-2, hPARP-2)|ADP-ribosyltransferase diphtheria toxin-like 2 (ARTD2)|DNA ADP-ribosyltransferase PARP2|NAD(+) ADP-ribosyltransferase 2 (ADPRT-2)|Poly[ADP-ribose] synthase 2 (pADPRT-2)|Protein poly-ADP-ribosyltransferase PARP2|PARP2|ADPRT2|ADPRTL2

Background: Involved in the base excision repair(BER) pathway, by catalyzing the poly(ADP-ribosyl)ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism. This modification follows DNA damages and appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks.

Gene ID: 10038

UniProt: Q9UGN5

Pathways: DNA Damage Repair